Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cylFcylF protein; Identified by match to PFAM protein family HMM PF01571; Belongs to the GcvT family. (317 aa)    
Predicted Functional Partners:
SAG1059
Glycine cleavage system H protein, putative; Identified by match to PFAM protein family HMM PF01597.
  
 0.996
cylG
cylG protein; Identified by match to PFAM protein family HMM PF00106.
   
 0.940
SAG0881
Acetoin dehydrogenase, thymine PPi dependent, E3 component, dihydrolipoamide dehydrogenase; Identified by match to PFAM protein family HMM PF00070.
 
 0.923
cylI
cylI protein; Identified by match to PFAM protein family HMM PF00109; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
  
  
 0.916
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.911
cylB
cylB protein.
     
 0.909
cylJ
cylJ protein; Similar to GP:6007854; identified by sequence similarity; putative.
     
 0.909
cylD
cylD protein.
  
  
 0.907
cylA
cylA protein; Identified by match to PFAM protein family HMM PF00005.
     
 0.904
cylK
cylK protein; Similar to GP:6007855; identified by sequence similarity; putative.
     
 0.900
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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