STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepQProline dipeptidase; Identified by match to PFAM protein family HMM PF00557; Belongs to the peptidase M24B family. (361 aa)    
Predicted Functional Partners:
pepO
Identified by match to PFAM protein family HMM PF01431.
   
 
 0.887
pepT
Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family.
  
 
 0.879
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
   0.828
cylF
cylF protein; Identified by match to PFAM protein family HMM PF01571; Belongs to the GcvT family.
  
 0.752
SAG0707
Transcriptional regulator, RegM family; Identified by match to PFAM protein family HMM PF00356.
  
 
 0.729
SAG0426
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.673
SAG1201
Iminodiacetate oxidase, putative; Identified by match to PFAM protein family HMM PF01266.
  
 
 0.667
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
    
  0.651
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
    
  0.651
SAG1666
Membrane protein, putative; Identified by match to PFAM protein family HMM PF00892.
    
 0.625
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.