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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coiACompetence protein CoiA; Similar to OMNI:SP0978; identified by sequence similarity; putative. (315 aa)    
Predicted Functional Partners:
pepB
Oligoendopeptidase B; Has oligopeptidase activity and degrades a variety of small bioactive peptides, including bradykinin, neurotensin, and peptide fragments of substance P and adrenocorticotropin. Also hydrolyzes the synthetic collagen-like substrate N-(3-[2-furyl]acryloyl)-Leu-Gly-Pro- Ala (FALGPA).
       0.763
dprA
DprA/SMF protein, putative DNA processing factor; Identified by match to PFAM protein family HMM PF02481.
  
  
 0.754
SAG0167
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.747
mecA
Negative regulator of competence MecA, putative; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
 
     0.709
SAG1193
TPR domain protein; Identified by match to PFAM protein family HMM PF00515.
  
     0.703
dnaI
Primosomal protein DnaI.
  
   
 0.701
ezrA
Septation ring formation regulator EzrA, putative; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
     0.700
SAG0803
Identified by match to PFAM protein family HMM PF00083.
       0.610
prsA
Protease maturation protein, putative; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins.
 
     0.607
gpsB
Conserved hypothetical protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
  
     0.563
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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