close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SAG0806Hydrolase, haloacid dehalogenase-like family; Identified by match to PFAM protein family HMM PF00702. (208 aa)    
Predicted Functional Partners:
SAG0192
PTS system, IIABC components; Identified by match to PFAM protein family HMM PF00358.
  
 
  0.839
SAG0790
PTS system, beta-glucosides-specific IIABC components; Identified by match to PFAM protein family HMM PF00358.
  
 
  0.839
SAG1690
PTS system, IIABC components; Identified by match to PFAM protein family HMM PF00358.
  
 
  0.839
SAG1959
PTS system, IIABC components; Identified by match to PFAM protein family HMM PF00358.
  
 
  0.839
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.822
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
  0.810
SAG0282
PTS system, IIBC components; Identified by match to PFAM protein family HMM PF00367.
    
  0.756
SAG0807
Identified by match to PFAM protein family HMM PF01596.
       0.616
prsA
Protease maturation protein, putative; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins.
  
    0.519
pepB
Oligoendopeptidase B; Has oligopeptidase activity and degrades a variety of small bioactive peptides, including bradykinin, neurotensin, and peptide fragments of substance P and adrenocorticotropin. Also hydrolyzes the synthetic collagen-like substrate N-(3-[2-furyl]acryloyl)-Leu-Gly-Pro- Ala (FALGPA).
       0.512
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
Server load: low (24%) [HD]