Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SAG0807Identified by match to PFAM protein family HMM PF01596. (235 aa)    
Predicted Functional Partners:
adhE
Aldehyde-alcohol dehydrogenase; Identified by match to PFAM protein family HMM PF00171; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
  0.787
SAG0741
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
  
 0.751
prsA
Protease maturation protein, putative; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins.
       0.720
SAG0742
Peptidase, U32 family; Identified by match to PFAM protein family HMM PF01136.
 
  
 0.718
SAG0806
Hydrolase, haloacid dehalogenase-like family; Identified by match to PFAM protein family HMM PF00702.
       0.704
SAG0809
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
     0.619
pepB
Oligoendopeptidase B; Has oligopeptidase activity and degrades a variety of small bioactive peptides, including bradykinin, neurotensin, and peptide fragments of substance P and adrenocorticotropin. Also hydrolyzes the synthetic collagen-like substrate N-(3-[2-furyl]acryloyl)-Leu-Gly-Pro- Ala (FALGPA).
       0.563
coiA
Competence protein CoiA; Similar to OMNI:SP0978; identified by sequence similarity; putative.
       0.554
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
       0.552
SAG0754
Conserved domain protein.
 
 
 0.498
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
Server load: low (20%) [HD]