Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
udkUridine kinase; Identified by match to PFAM protein family HMM PF00485. (209 aa)    
Predicted Functional Partners:
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
 
 0.999
cmk
Cytidylate kinase; Identified by match to PFAM protein family HMM PF02224.
   
 
 0.962
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
    
 0.959
pyrR
Pyrimidine operon regulatory protein; Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
     
 0.957
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.933
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.924
SAG1566
D-isomer specific 2-hydroxyacid dehydrogenase family protein; Identified by match to PFAM protein family HMM PF01842; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
  0.875
SAG0528
Inosine-uridine preferring nucleoside hydrolase; Identified by match to PFAM protein family HMM PF01156.
  
 0.841
gap
Glyceraldehyde 3-phosphate dehydrogenase; Identified by match to PFAM protein family HMM PF00044; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.829
cpdB
2',3'-cyclic-nucleotide 2'-phosphodiesterase; Identified by match to PFAM protein family HMM PF00149.
  
 
  0.824
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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