Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SAG0878Acetoin dehydrogenase, thymine PPi dependent, E1 component, alpha subunit; Identified by match to PFAM protein family HMM PF00676. (322 aa)    
Predicted Functional Partners:
SAG0879
Acetoin dehydrogenase, thymine PPi dependent, E1 component, beta subunit; Identified by match to PFAM protein family HMM PF02779.
 0.999
SAG0880
Acetoin dehydrogenase, thymine PPi dependent, E2 component, dihydrolipoamide acetyltransferase; Identified by match to PFAM protein family HMM PF00198.
 
 0.999
SAG0881
Acetoin dehydrogenase, thymine PPi dependent, E3 component, dihydrolipoamide dehydrogenase; Identified by match to PFAM protein family HMM PF00070.
 
 0.998
fba
Fructose-bisphosphate aldolase; Identified by match to PFAM protein family HMM PF01116.
  
 
 0.937
pflD-2
Formate acetyltransferase; Identified by match to PFAM protein family HMM PF01228.
   
 
 0.927
ilvK
Acetolactate synthase, catabolic; Identified by match to PFAM protein family HMM PF00205; Belongs to the TPP enzyme family.
  
 
 0.926
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 
 0.924
pyk
Pyruvate kinase; Identified by match to PFAM protein family HMM PF00224; Belongs to the pyruvate kinase family.
  
 
 0.924
ppdK
Pyruvate phosphate dikinase; Identified by match to PFAM protein family HMM PF00391; Belongs to the PEP-utilizing enzyme family.
    
 0.922
pgi
Glucose-6-phosphate isomerase; Identified by match to PFAM protein family HMM PF00342.
    
 0.921
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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