Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SAG1016Response regulator; Identified by match to PFAM protein family HMM PF00072. (244 aa)    
Predicted Functional Partners:
SAG1017
Sensor histidine kinase, putative; Identified by match to PFAM protein family HMM PF02518.
 
 0.986
lytS
Sensor histidine kinase, putative; Member of the two-component regulatory system LytR/LytS that probably regulates genes involved in cell wall metabolism.
 
 0.947
SAG1947
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
 
 0.886
SAG1921
Sensor histidine kinase; Similar to OMNI:NTL01SPL0863; identified by sequence similarity; putative.
 
 
 0.743
SAG1015
Carbon starvation protein CstA, putative.
 
   
 0.604
SAG1922
Response regulator; Identified by match to PFAM protein family HMM PF00072.
  
  
 0.549
SAG0185
Membrane protein, putative.
   
 0.484
SAG0184
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
   
 0.476
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
   0.450
SAG1946
DNA-binding response regulator; Identified by match to PFAM protein family HMM PF00072.
  
 
 0.438
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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