Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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SAG1091Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to PFAM protein family HMM PF00106; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (216 aa)    
Predicted Functional Partners:
SAG1209
Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to PFAM protein family HMM PF00106; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  
0.560
dltA
D-alanine-activating enzyme; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent AMP [...]
 
 
  0.501
SAG1092
Phosphate acetyltransferase; Identified by match to PFAM protein family HMM PF01515.
       0.491
kup
Potassium uptake protein, putative; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family.
       0.490
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
    
 0.489
SAG1756
Conserved hypothetical protein; Identified by Glimmer2; putative.
    
 0.482
SAG1433
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
 
 0.470
nadK
Conserved hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
       0.465
psaD
Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.
   
    0.458
SAG1803
Carbohydrate kinase, FGGY family; Identified by match to PFAM protein family HMM PF00370; Belongs to the FGGY kinase family.
    
  0.440
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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