Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
rexConserved hypothetical protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (210 aa)    
Predicted Functional Partners:
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
   
    0.865
adhE
Aldehyde-alcohol dehydrogenase; Identified by match to PFAM protein family HMM PF00171; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.666
prsA-2
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
       0.642
iscS-1
Cysteine desulphurase; Identified by match to PFAM protein family HMM PF00266.
       0.642
SAG1099
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.642
radC
DNA repair protein RadC; Identified by match to TIGR protein family HMM TIGR00608; Belongs to the UPF0758 family.
     
 0.630
nox-2
NADH oxidase; Identified by match to PFAM protein family HMM PF00070.
      
 0.616
SAG1092
Phosphate acetyltransferase; Identified by match to PFAM protein family HMM PF01515.
     
 0.589
SAG1096
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.536
SAG0522
Metallo-beta-lactamase superfamily protein; Identified by match to PFAM protein family HMM PF00753.
 
   
 0.532
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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