Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SAG1106Transcriptional regulator, AraC family; Identified by match to PFAM protein family HMM PF00165. (309 aa)    
Predicted Functional Partners:
ribA
Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.701
SAG1528
Chorismate binding enzyme; Identified by match to PFAM protein family HMM PF00425.
    
 0.694
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.600
SAG1947
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
  
  0.461
SAG0698
Beta-glucuronidase; Identified by match to PFAM protein family HMM PF00703; Belongs to the glycosyl hydrolase 2 family.
    
 0.417
SAG0466
Thiolase; Identified by match to PFAM protein family HMM PF00108; Belongs to the thiolase-like superfamily. Thiolase family.
     
 0.416
glmS
Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
   
 
 0.409
SAG2128
Response regulator; Identified by match to PFAM protein family HMM PF00072.
  
  
 0.404
SAG0691
Transcriptional regulator, LysR family; Identified by match to PFAM protein family HMM PF00126; Belongs to the LysR transcriptional regulatory family.
  
  
 0.403
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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