close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
potASpermidine/putrescine ABC transporter, ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (384 aa)    
Predicted Functional Partners:
potD
Spermidine/putrescine ABC transporter, spermidine/putrescine-binding protein; Identified by match to PFAM protein family HMM PF01547.
 
 
 0.999
potC
Spermidine/putrescine ABC transporter, permease protein; Identified by match to PFAM protein family HMM PF00528.
 
 
 0.999
potB
Spermidine/putrescine ABC transporter, permease protein; Identified by match to PFAM protein family HMM PF00528.
 
 0.999
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
  
  
 0.903
SAG2130
Amino acid ABC transporter, amino acid-binding protein/permease protein; Identified by match to PFAM protein family HMM PF00528.
  
 
 0.902
SAG1796
Amino acid ABC transporter, permease protein; Identified by match to PFAM protein family HMM PF00528.
   
 0.835
SAG1945
Iron ABC transporter, iron-binding protein; Identified by match to PFAM protein family HMM PF01547.
  
 
 0.830
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by match to PFAM protein family HMM PF01288.
     
 0.802
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.729
SAG1925
Sugar ABC transporter, ATP-binding protein; Identified by match to PFAM protein family HMM PF00005; Belongs to the ABC transporter superfamily.
 
 
 
0.680
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
Server load: medium (52%) [HD]