STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SAG1490Transcriptional regulator, MutR family; Identified by match to PFAM protein family HMM PF01381. (282 aa)    
Predicted Functional Partners:
SAG0277
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.714
lacD
Tagatose 1,6-diphosphate aldolase; Identified by match to TIGR protein family HMM TIGR01232; Belongs to the aldolase LacD family.
  
 
  0.669
SAG2068
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.642
SAG1683
Immunogenic secreted protein, putative; Similar to GP:1399011; identified by sequence similarity; putative.
  
     0.547
SAG0267
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
     0.546
SAG1356
Transcriptional regulator, RofA family; Similar to GB:U01312 PID:460083; identified by sequence similarity; putative.
   
  
 0.536
SAG1359
Permease, putative; Identified by match to PFAM protein family HMM PF02687.
  
  
 0.531
SAG0013
Protein of unknown function; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.
  
     0.514
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
       0.483
mutM
formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.483
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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