node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SAG0801 | exoA | SAG0801 | SAG1563 | Ribosomal small subunit pseudouridine synthase A, putative; Identified by match to PFAM protein family HMM PF00849; Belongs to the pseudouridine synthase RsuA family. | Exodeoxyribonuclease; Identified by match to PFAM protein family HMM PF01260; In Gram negative bacteria, the apparent functional equivalent is known as exodeoxyribonuclease III (xth). | 0.657 |
SAG1574 | dnaN | SAG1574 | SAG0002 | DNA polymerase III, delta prime subunit, putative. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.998 |
SAG1574 | exoA | SAG1574 | SAG1563 | DNA polymerase III, delta prime subunit, putative. | Exodeoxyribonuclease; Identified by match to PFAM protein family HMM PF01260; In Gram negative bacteria, the apparent functional equivalent is known as exodeoxyribonuclease III (xth). | 0.778 |
SAG1574 | polA | SAG1574 | SAG0389 | DNA polymerase III, delta prime subunit, putative. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.957 |
birA | exoA | SAG0830 | SAG1563 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Exodeoxyribonuclease; Identified by match to PFAM protein family HMM PF01260; In Gram negative bacteria, the apparent functional equivalent is known as exodeoxyribonuclease III (xth). | 0.888 |
birA | mutY | SAG0830 | SAG1715 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.489 |
birA | tadA | SAG0830 | SAG0400 | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Cytidine/deoxycytidylate deaminase family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.957 |
dnaN | SAG1574 | SAG0002 | SAG1574 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III, delta prime subunit, putative. | 0.998 |
dnaN | exoA | SAG0002 | SAG1563 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease; Identified by match to PFAM protein family HMM PF01260; In Gram negative bacteria, the apparent functional equivalent is known as exodeoxyribonuclease III (xth). | 0.940 |
dnaN | mutY | SAG0002 | SAG1715 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.870 |
dnaN | polA | SAG0002 | SAG0389 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.999 |
dnaN | ung | SAG0002 | SAG1156 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.812 |
exoA | SAG0801 | SAG1563 | SAG0801 | Exodeoxyribonuclease; Identified by match to PFAM protein family HMM PF01260; In Gram negative bacteria, the apparent functional equivalent is known as exodeoxyribonuclease III (xth). | Ribosomal small subunit pseudouridine synthase A, putative; Identified by match to PFAM protein family HMM PF00849; Belongs to the pseudouridine synthase RsuA family. | 0.657 |
exoA | SAG1574 | SAG1563 | SAG1574 | Exodeoxyribonuclease; Identified by match to PFAM protein family HMM PF01260; In Gram negative bacteria, the apparent functional equivalent is known as exodeoxyribonuclease III (xth). | DNA polymerase III, delta prime subunit, putative. | 0.778 |
exoA | birA | SAG1563 | SAG0830 | Exodeoxyribonuclease; Identified by match to PFAM protein family HMM PF01260; In Gram negative bacteria, the apparent functional equivalent is known as exodeoxyribonuclease III (xth). | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.888 |
exoA | dnaN | SAG1563 | SAG0002 | Exodeoxyribonuclease; Identified by match to PFAM protein family HMM PF01260; In Gram negative bacteria, the apparent functional equivalent is known as exodeoxyribonuclease III (xth). | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.940 |
exoA | mutY | SAG1563 | SAG1715 | Exodeoxyribonuclease; Identified by match to PFAM protein family HMM PF01260; In Gram negative bacteria, the apparent functional equivalent is known as exodeoxyribonuclease III (xth). | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.920 |
exoA | nth | SAG1563 | SAG0468 | Exodeoxyribonuclease; Identified by match to PFAM protein family HMM PF01260; In Gram negative bacteria, the apparent functional equivalent is known as exodeoxyribonuclease III (xth). | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.985 |
exoA | polA | SAG1563 | SAG0389 | Exodeoxyribonuclease; Identified by match to PFAM protein family HMM PF01260; In Gram negative bacteria, the apparent functional equivalent is known as exodeoxyribonuclease III (xth). | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.931 |
exoA | rsuA | SAG1563 | SAG1475 | Exodeoxyribonuclease; Identified by match to PFAM protein family HMM PF01260; In Gram negative bacteria, the apparent functional equivalent is known as exodeoxyribonuclease III (xth). | Ribosomal small subunit pseudouridine synthase A; Identified by match to PFAM protein family HMM PF00849; Belongs to the pseudouridine synthase RsuA family. | 0.818 |