Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
csrSSensor histidine kinase CsrS; Identified by match to PFAM protein family HMM PF00512. (501 aa)    
Predicted Functional Partners:
csrR
DNA-binding response regulator CsrR; Identified by match to PFAM protein family HMM PF00072.
 
 0.998
SAG1328
DNA-binding response regulator; Identified by match to PFAM protein family HMM PF00072.
 
 0.900
dltR
DNA-binding response regulator; Member of the two-component regulatory system DltS/DltR. Regulates the expression of the dlt operon.
 
 0.900
SAG0719
DNA-binding response regulator; Identified by match to PFAM protein family HMM PF00072.
 
 0.899
SAG2122
DNA-binding response regulator; Identified by match to PFAM protein family HMM PF00072.
 
 0.898
SAG0123
DNA-binding response regulator; Identified by match to PFAM protein family HMM PF00072.
 
 0.893
SAG0393
DNA-binding response regulator; Identified by match to PFAM protein family HMM PF00072.
 
 0.886
SAG0881
Acetoin dehydrogenase, thymine PPi dependent, E3 component, dihydrolipoamide dehydrogenase; Identified by match to PFAM protein family HMM PF00070.
    
 0.882
ciaR
DNA-binding response regulator CiaR; Identified by match to PFAM protein family HMM PF00072.
 
 0.873
SAG0712
DNA-binding response regulator; Identified by match to PFAM protein family HMM PF00072.
 
 0.868
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
Server load: low (10%) [HD]