Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SAG1673Identified by match to PFAM protein family HMM PF00725. (321 aa)    
Predicted Functional Partners:
SAG0466
Thiolase; Identified by match to PFAM protein family HMM PF00108; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.999
SAG0342
Identified by match to PFAM protein family HMM PF00378.
 0.991
SAG1316
HMG-CoA synthase; Identified by match to PFAM protein family HMM PF01154.
     
  0.904
adhE
Aldehyde-alcohol dehydrogenase; Identified by match to PFAM protein family HMM PF00171; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.638
clpP
ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
  0.620
SAG1092
Phosphate acetyltransferase; Identified by match to PFAM protein family HMM PF01515.
    
 0.612
SAG0523
Oxidoreductase, short chain dehydrogenase/reductase family; Identified by match to PFAM protein family HMM PF00106.
 
 0.565
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
      
 0.560
clpX
ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
  
 
  0.527
SAG0881
Acetoin dehydrogenase, thymine PPi dependent, E3 component, dihydrolipoamide dehydrogenase; Identified by match to PFAM protein family HMM PF00070.
  
 
 0.514
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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