Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
talTransaldolase family protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (215 aa)    
Predicted Functional Partners:
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.995
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.974
pgi
Glucose-6-phosphate isomerase; Identified by match to PFAM protein family HMM PF00342.
  
 0.967
SAG0199
Transketolase, N-terminal subunit; Identified by match to PFAM protein family HMM PF00456.
 
  
 0.959
fba
Fructose-bisphosphate aldolase; Identified by match to PFAM protein family HMM PF01116.
  
 0.957
SAG0200
Transketolase, C-terminal subunit; Identified by match to PFAM protein family HMM PF02779.
  
 
 0.954
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 0.953
gap
Glyceraldehyde 3-phosphate dehydrogenase; Identified by match to PFAM protein family HMM PF00044; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 0.948
pyk
Pyruvate kinase; Identified by match to PFAM protein family HMM PF00224; Belongs to the pyruvate kinase family.
  
 0.935
gpmA
Phosphoglycerate mutase family protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 0.926
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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