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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SAG1906Carbohydrate kinase, PfkB family; Identified by match to PFAM protein family HMM PF00294. (335 aa)    
Predicted Functional Partners:
eda-2
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Identified by match to PFAM protein family HMM PF01081.
 
 0.986
SAG1346
PTS system, fructose specific IIABC components; Identified by match to PFAM protein family HMM PF00359.
  
 
 0.926
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.884
eda-1
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Identified by match to PFAM protein family HMM PF01081.
 
 
 0.882
SAG1904
Oxidoreductase, short-chain dehydrogenase/reductase family; Identified by match to PFAM protein family HMM PF00106.
 
 0.867
SAG1905
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
 
 0.840
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.839
manL
PTS system, mannose-specific IIAB components.
  
 
 0.811
rpe
Ribulose-phosphate 3-epimerase; Identified by match to PFAM protein family HMM PF00834; Belongs to the ribulose-phosphate 3-epimerase family.
  
 0.803
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family.
 
  
 0.778
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.