STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eda-22-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Identified by match to PFAM protein family HMM PF01081. (212 aa)    
Predicted Functional Partners:
SAG1906
Carbohydrate kinase, PfkB family; Identified by match to PFAM protein family HMM PF00294.
 
 0.997
SAG0697
2-keto-3-deoxygluconate kinase; Identified by match to PFAM protein family HMM PF00294.
 
 0.996
gap
Glyceraldehyde 3-phosphate dehydrogenase; Identified by match to PFAM protein family HMM PF00044; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.923
pgi
Glucose-6-phosphate isomerase; Identified by match to PFAM protein family HMM PF00342.
  
 
 0.922
pyk
Pyruvate kinase; Identified by match to PFAM protein family HMM PF00224; Belongs to the pyruvate kinase family.
    
 0.919
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
     
 0.915
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
     
 0.913
fba
Fructose-bisphosphate aldolase; Identified by match to PFAM protein family HMM PF01116.
    
 0.912
ppdK
Pyruvate phosphate dikinase; Identified by match to PFAM protein family HMM PF00391; Belongs to the PEP-utilizing enzyme family.
     
 0.912
SAG1959
PTS system, IIABC components; Identified by match to PFAM protein family HMM PF00358.
    
 0.911
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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