Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SAG1922Response regulator; Identified by match to PFAM protein family HMM PF00072. (229 aa)    
Predicted Functional Partners:
SAG1921
Sensor histidine kinase; Similar to OMNI:NTL01SPL0863; identified by sequence similarity; putative.
 
 0.996
SAG1920
Citrate carrier protein, CCS family; Identified by match to PFAM protein family HMM PF03390.
 
  
 0.771
SAG1946
DNA-binding response regulator; Identified by match to PFAM protein family HMM PF00072.
  
  
 0.585
SAG2128
Response regulator; Identified by match to PFAM protein family HMM PF00072.
 
  
 0.578
SAG1016
Response regulator; Identified by match to PFAM protein family HMM PF00072.
  
  
 0.549
SAG1919
Malate oxidoreductase; Identified by match to PFAM protein family HMM PF00390.
  
    0.539
lytR
Response regulator; Member of the two-component regulatory system LytR/LytS that probably regulates genes involved in cell wall metabolism.
  
  
 0.524
SAG0394
Sensor histidine kinase; Identified by match to PFAM protein family HMM PF00512.
 
  
 0.483
SAG2127
Sensor histidine kinase; Identified by match to PFAM protein family HMM PF02518.
 
  
 0.415
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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