Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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galEUDP-glucose 4-epimerase; Identified by match to PFAM protein family HMM PF01370; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (331 aa)    
Predicted Functional Partners:
galU
UTP-glucose-1-phosphate uridylyltransferase; Identified by match to PFAM protein family HMM PF00483.
 
  
 0.985
SAG1753
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
 0.964
glmU
UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family.
   
 0.946
rfbA
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
    
 0.929
lacC
Tagatose-6-phosphate kinase; Identified by match to PFAM protein family HMM PF00294; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
     
 0.863
SAG1416
Nucleotide sugar dehydratase, putative.
 
 0.822
lacD
Tagatose 1,6-diphosphate aldolase; Identified by match to TIGR protein family HMM TIGR01232; Belongs to the aldolase LacD family.
     
 0.755
pgm
Phosphoglucomutase; Identified by match to PFAM protein family HMM PF00408.
 
 0.716
dexB
Glucan 1,6-alpha-glucosidase; Identified by match to PFAM protein family HMM PF00128.
  
 
 0.705
rfbB
dTDP-glucose 4,6-dehydratase; Identified by match to PFAM protein family HMM PF01370; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
 
 0.699
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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