Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lacDTagatose 1,6-diphosphate aldolase; Identified by match to TIGR protein family HMM TIGR01232; Belongs to the aldolase LacD family. (325 aa)    
Predicted Functional Partners:
lacC
Tagatose-6-phosphate kinase; Identified by match to PFAM protein family HMM PF00294; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
 
 0.999
lacB
Galactose-6-phosphate isomerase, LacB subunit; Identified by match to PFAM protein family HMM PF02502.
 
  
 0.982
lacA
Galactose-6-phosphate isomerase, LacA subunit; Identified by match to PFAM protein family HMM PF02502.
 
  
 0.967
pfk
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.918
gapN
Glyceraldehyde-3-phosphate dehydrogenase, NADP-dependent; Identified by match to PFAM protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.
     
  0.904
eda-2
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Identified by match to PFAM protein family HMM PF01081.
     
  0.904
SAG1927
lacX protein; Identified by match to PFAM protein family HMM PF02693.
  
  
 0.844
fruK
1-phosphofructokinase; Identified by match to PFAM protein family HMM PF00294; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
  
 
 0.819
lacR-2
Lactose phosphotransferase system repressor; Identified by match to PFAM protein family HMM PF00455.
 
   
 0.800
SAG1933
PTS system, IIC component, putative.
 
  
  0.773
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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