Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lacAGalactose-6-phosphate isomerase, LacA subunit; Identified by match to PFAM protein family HMM PF02502. (141 aa)    
Predicted Functional Partners:
lacB
Galactose-6-phosphate isomerase, LacB subunit; Identified by match to PFAM protein family HMM PF02502.
 
 0.999
lacC
Tagatose-6-phosphate kinase; Identified by match to PFAM protein family HMM PF00294; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
  
 
 0.998
lacD
Tagatose 1,6-diphosphate aldolase; Identified by match to TIGR protein family HMM TIGR01232; Belongs to the aldolase LacD family.
 
  
 0.967
pfk
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
 
 0.922
bglA
6-phospho-beta-glucosidase; Identified by match to PFAM protein family HMM PF00232; Belongs to the glycosyl hydrolase 1 family.
  
 
 0.862
fruK
1-phosphofructokinase; Identified by match to PFAM protein family HMM PF00294; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
  
 
 0.814
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
 
 0.806
SAG1927
lacX protein; Identified by match to PFAM protein family HMM PF02693.
  
  
 0.755
ascB
6-phospho-beta-glucosidase; Identified by match to PFAM protein family HMM PF00232; Belongs to the glycosyl hydrolase 1 family.
  
 
 0.735
SAG1934
PTS system, IIB component, putative; Similar to OMNI:NTL01SPL1345; identified by sequence similarity; putative.
 
     0.727
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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