close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lacAGalactose-6-phosphate isomerase, LacA subunit; Identified by match to PFAM protein family HMM PF02502. (141 aa)    
Predicted Functional Partners:
lacB
Galactose-6-phosphate isomerase, LacB subunit; Identified by match to PFAM protein family HMM PF02502.
 
 0.999
lacC
Tagatose-6-phosphate kinase; Identified by match to PFAM protein family HMM PF00294; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
  
 
 0.993
lacD
Tagatose 1,6-diphosphate aldolase; Identified by match to TIGR protein family HMM TIGR01232; Belongs to the aldolase LacD family.
 
  
 0.963
fruK
1-phosphofructokinase; Identified by match to PFAM protein family HMM PF00294; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
  
 
 0.831
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
 
  0.820
bglA
6-phospho-beta-glucosidase; Identified by match to PFAM protein family HMM PF00232; Belongs to the glycosyl hydrolase 1 family.
  
 
 0.815
SAG2048
5-methyltetrahydrofolate--homocysteine methyltransferase, putative; Identified by match to PFAM protein family HMM PF02219.
    
  0.806
lacR-2
Lactose phosphotransferase system repressor; Identified by match to PFAM protein family HMM PF00455.
 
 
 0.771
galE
UDP-glucose 4-epimerase; Identified by match to PFAM protein family HMM PF01370; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
  
  
 0.743
glk
Glucokinase; Identified by match to PFAM protein family HMM PF00480.
  
 
 0.730
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.