Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SAG1932Identified by match to PFAM protein family HMM PF02012. (816 aa)    
Predicted Functional Partners:
lacD
Tagatose 1,6-diphosphate aldolase; Identified by match to TIGR protein family HMM TIGR01232; Belongs to the aldolase LacD family.
     
 0.750
rplL
Ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.
      
 0.559
SAG1104
Platelet activating factor, putative.
 
  
  0.522
SAG0698
Beta-glucuronidase; Identified by match to PFAM protein family HMM PF00703; Belongs to the glycosyl hydrolase 2 family.
    
 0.510
SAG0039
N-acetylneuraminate lyase, putative; Identified by match to PFAM protein family HMM PF00701.
 
   
 0.499
accC
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
   
    0.451
SAG1933
PTS system, IIC component, putative.
       0.427
SAG1901
Glucuronyl hydrolase; Similar to GP:5869507; identified by sequence similarity; putative.
     
  0.426
lacA
Galactose-6-phosphate isomerase, LacA subunit; Identified by match to PFAM protein family HMM PF02502.
       0.423
neuA
CMP-N-acetylneuraminic acid synthetase NeuA; Catalyzes the formation of CMP-N-acetylneuraminic acid (CMP- NeuNAc), which is essential for the formation of the capsule. Belongs to the CMP-NeuNAc synthase family.
    
  0.403
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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