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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cpdB2',3'-cyclic-nucleotide 2'-phosphodiesterase; Identified by match to PFAM protein family HMM PF00149. (800 aa)    
Predicted Functional Partners:
SAG1333
Identified by match to PFAM protein family HMM PF00149; Belongs to the 5'-nucleotidase family.
 
  
 
0.956
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.857
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.857
tdk
Thymidine kinases; Identified by match to PFAM protein family HMM PF00265.
 
  
  0.740
add
Adenosine deaminase, putative; Identified by match to PFAM protein family HMM PF00962; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
 
  
 0.723
SAG1944
Conserved hypothetical protein; Identified by Glimmer2; putative.
    
  0.690
SAG1974
Identified by match to PFAM protein family HMM PF00293.
 
  
  0.685
hpt
Hypoxanthine-guanine phosphoribosyltransferase; Identified by match to PFAM protein family HMM PF00156.
  
  
 0.661
deoD-2
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.661
purB
Adenylosuccinate lyase; Identified by match to PFAM protein family HMM PF00206; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 
 0.650
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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