Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nrdI-2nrdI protein; Identified by match to TIGR protein family HMM TIGR00333; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002; Belongs to the NrdI family. (151 aa)    
Predicted Functional Partners:
nrdF-2
Ribonucleoside-diphosphate reductase 2, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
 
 0.990
nrdF-1
Ribonucleoside-diphosphate reductase 2, beta subunit; Identified by match to PFAM protein family HMM PF00268.
 
 0.986
nrdH
Ribonucleoside-diphosphate reductase 2, NrdH-redoxin.
 
  
 0.954
nrdE-2
Ribonucleoside-diphosphate reductase 2, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
  
 0.949
nrdE-1
Ribonucleoside-diphosphate reductase 2, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
  
 0.924
SAG1943
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.830
SAG1944
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.830
SAG1940
GTP pyrophosphokinase family protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
 0.729
dtd
Protein of unknown function TIGR00256; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DT [...]
       0.532
cpdB
2',3'-cyclic-nucleotide 2'-phosphodiesterase; Identified by match to PFAM protein family HMM PF00149.
       0.520
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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