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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SAG1946DNA-binding response regulator; Identified by match to PFAM protein family HMM PF00072. (257 aa)    
Predicted Functional Partners:
SAG1947
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
 
 0.984
SAG1945
Iron ABC transporter, iron-binding protein; Identified by match to PFAM protein family HMM PF01547.
 
     0.911
SAG0394
Sensor histidine kinase; Identified by match to PFAM protein family HMM PF00512.
 
  
 0.893
SAG0124
Sensor histidine kinase; Identified by match to PFAM protein family HMM PF00512.
 
  
  0.750
SAG0322
DNA-binding response regulator; Identified by match to PFAM protein family HMM PF00072.
 
  
 0.713
SAG1922
Response regulator; Identified by match to PFAM protein family HMM PF00072.
  
  
 0.713
SAG2128
Response regulator; Identified by match to PFAM protein family HMM PF00072.
    
 0.688
SAG0644
Transcriptional regulator, AraC family; Identified by match to PFAM protein family HMM PF00165.
 
  
  0.684
pyk
Pyruvate kinase; Identified by match to PFAM protein family HMM PF00224; Belongs to the pyruvate kinase family.
    
  0.607
SAG1017
Sensor histidine kinase, putative; Identified by match to PFAM protein family HMM PF02518.
 
 
 0.573
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.