Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SAG1948PTS system, IID component. (275 aa)    
Predicted Functional Partners:
manL
PTS system, mannose-specific IIAB components.
 
 0.999
SAG1949
PTS system, IIC component.
 0.998
manM
PTS system, mannose-specific IIC component.
 0.997
SAG1951
PTS system, IIA component, putative.
 
 0.997
SAG1950
PTS system, IIB component.
 
 0.992
SAG1899
PTS system, IIC component.
 
 0.980
SAG1902
PTS system, IIA component.
 
 0.972
SAG1900
PTS system, IIB component.
 
 0.959
SAG1346
PTS system, fructose specific IIABC components; Identified by match to PFAM protein family HMM PF00359.
  
 
 0.938
SAG0359
PTS system, mannose-specific IID component.
  
  
 
0.923
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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