STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SAG1952Membrane protein, putative; Similar to GP:7960293; identified by sequence similarity; putative. (353 aa)    
Predicted Functional Partners:
gshAB
Glutamate--cysteine ligase/amino acid ligase, putative; Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine.
  
 
 0.921
SAG0025
Phosphoribosylformylglycinamidine synthase, putative; Identified by match to PFAM protein family HMM PF02769.
    
 0.898
ddl
D-alanine--D-alanine ligase; Cell wall formation.
  
 
 0.769
glnA
Glutamine synthetase, type I; Identified by match to PFAM protein family HMM PF00120; Belongs to the glutamine synthetase family.
     
 0.727
dltA
D-alanine-activating enzyme; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent AMP [...]
    
 0.721
gdhA
NADP-specific glutamate dehydrogenase; Identified by match to PFAM protein family HMM PF00208; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.696
fibA
Beta-lactam resistance factor; Identified by match to PFAM protein family HMM PF02388.
 
     0.608
SAG0366
Conserved hypothetical protein TIGR00150; Identified by Glimmer2; putative.
  
 
  0.607
SAG0510
murM protein, putative; Identified by match to PFAM protein family HMM PF02388.
 
     0.588
SAG1953
Hypothetical protein; Identified by Glimmer2; putative.
       0.567
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.