Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
SAG2000Membrane protein, putative; Similar to GP:6782407; identified by sequence similarity; putative. (666 aa)    
Predicted Functional Partners:
SAG2001
Conjugal transfer protein, interruption-C; This gene is interrupted by an IS1381 element.
       0.820
SAG2002
IS1381, transposase OrfB; Identified by match to PFAM protein family HMM PF01609.
       0.603
SAG2003
IS1381, transposase OrfA; Similar to OMNI:SP0537; identified by sequence similarity; putative.
       0.528
SAG2006
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.483
SAG2005
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.481
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
 
 0.461
secY2
Preprotein translocase SecY family protein; Part of the accessory SecA2/SecY2 system specifically required for export of possible cell wall proteins. The central subunit of a protein translocation channel.
   
 
 0.461
SAG0460
ABC transporter, ATP-binding/permease protein; Identified by match to PFAM protein family HMM PF00005.
   
   0.410
SAG0461
ABC transporter, ATP-binding/permease protein; Identified by match to PFAM protein family HMM PF00005.
   
   0.410
SAG1070
ABC transporter, ATP-binding/permease protein; Identified by match to PFAM protein family HMM PF00005.
   
   0.410
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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