SAG2003 protein (Streptococcus agalactiae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SAG2003

IS1381, transposase OrfA; Similar to OMNI:SP0537; identified by sequence similarity; putative. (127 aa)

Predicted Functional Partners:

SAG2002

0.922

guaA

0.813

SAG0261

0.774

SAG0543

0.774

SAG0966

0.774

SAG1457

0.774

SAG1550

0.774

guaB

0.763

SAG2001

0.552

SAG2000

0.528

Your Current Organism:

Streptococcus agalactiae

NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SAG0261	SAG2003	SAG0261	SAG2003	IS1381, transposase OrfB; Identified by match to PFAM protein family HMM PF01609.	IS1381, transposase OrfA; Similar to OMNI:SP0537; identified by sequence similarity; putative.	0.774
SAG0261	guaA	SAG0261	SAG0967	IS1381, transposase OrfB; Identified by match to PFAM protein family HMM PF01609.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.813
SAG0261	guaB	SAG0261	SAG2159	IS1381, transposase OrfB; Identified by match to PFAM protein family HMM PF01609.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.763
SAG0543	SAG2003	SAG0543	SAG2003	IS1381, transposase OrfB; Identified by match to PFAM protein family HMM PF01609.	IS1381, transposase OrfA; Similar to OMNI:SP0537; identified by sequence similarity; putative.	0.774
SAG0543	guaA	SAG0543	SAG0967	IS1381, transposase OrfB; Identified by match to PFAM protein family HMM PF01609.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.813
SAG0543	guaB	SAG0543	SAG2159	IS1381, transposase OrfB; Identified by match to PFAM protein family HMM PF01609.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.763
SAG0966	SAG2003	SAG0966	SAG2003	IS1381, transposase OrfB; Identified by match to PFAM protein family HMM PF01609.	IS1381, transposase OrfA; Similar to OMNI:SP0537; identified by sequence similarity; putative.	0.774
SAG0966	guaA	SAG0966	SAG0967	IS1381, transposase OrfB; Identified by match to PFAM protein family HMM PF01609.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.813
SAG0966	guaB	SAG0966	SAG2159	IS1381, transposase OrfB; Identified by match to PFAM protein family HMM PF01609.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.763
SAG1457	SAG2003	SAG1457	SAG2003	IS1381, transposase OrfB; Identified by match to PFAM protein family HMM PF01609.	IS1381, transposase OrfA; Similar to OMNI:SP0537; identified by sequence similarity; putative.	0.774
SAG1457	guaA	SAG1457	SAG0967	IS1381, transposase OrfB; Identified by match to PFAM protein family HMM PF01609.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.813
SAG1457	guaB	SAG1457	SAG2159	IS1381, transposase OrfB; Identified by match to PFAM protein family HMM PF01609.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.763
SAG1550	SAG2003	SAG1550	SAG2003	IS1381, transposase OrfB; Identified by match to PFAM protein family HMM PF01609.	IS1381, transposase OrfA; Similar to OMNI:SP0537; identified by sequence similarity; putative.	0.774
SAG1550	guaA	SAG1550	SAG0967	IS1381, transposase OrfB; Identified by match to PFAM protein family HMM PF01609.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.813
SAG1550	guaB	SAG1550	SAG2159	IS1381, transposase OrfB; Identified by match to PFAM protein family HMM PF01609.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.763
SAG2000	SAG2001	SAG2000	SAG2001	Membrane protein, putative; Similar to GP:6782407; identified by sequence similarity; putative.	Conjugal transfer protein, interruption-C; This gene is interrupted by an IS1381 element.	0.772
SAG2000	SAG2002	SAG2000	SAG2002	Membrane protein, putative; Similar to GP:6782407; identified by sequence similarity; putative.	IS1381, transposase OrfB; Identified by match to PFAM protein family HMM PF01609.	0.603
SAG2000	SAG2003	SAG2000	SAG2003	Membrane protein, putative; Similar to GP:6782407; identified by sequence similarity; putative.	IS1381, transposase OrfA; Similar to OMNI:SP0537; identified by sequence similarity; putative.	0.528
SAG2001	SAG2000	SAG2001	SAG2000	Conjugal transfer protein, interruption-C; This gene is interrupted by an IS1381 element.	Membrane protein, putative; Similar to GP:6782407; identified by sequence similarity; putative.	0.772
SAG2001	SAG2002	SAG2001	SAG2002	Conjugal transfer protein, interruption-C; This gene is interrupted by an IS1381 element.	IS1381, transposase OrfB; Identified by match to PFAM protein family HMM PF01609.	0.630

page 1 of 3

Server load: low (30%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About