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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SAG2127Sensor histidine kinase; Identified by match to PFAM protein family HMM PF02518. (431 aa)    
Predicted Functional Partners:
SAG0881
Acetoin dehydrogenase, thymine PPi dependent, E3 component, dihydrolipoamide dehydrogenase; Identified by match to PFAM protein family HMM PF00070.
    
 0.969
SAG2128
Response regulator; Identified by match to PFAM protein family HMM PF00072.
 
 
 0.967
SAG0394
Sensor histidine kinase; Identified by match to PFAM protein family HMM PF00512.
   
 0.818
rbsB
Ribose ABC transporter, periplasmic D-ribose-binding protein; Identified by match to PFAM protein family HMM PF00532.
    
 0.812
SAG0342
Identified by match to PFAM protein family HMM PF00378.
   
 0.799
SAG2124
Membrane protein, putative.
 
     0.783
SAG0880
Acetoin dehydrogenase, thymine PPi dependent, E2 component, dihydrolipoamide acetyltransferase; Identified by match to PFAM protein family HMM PF00198.
    
 0.712
SAG0879
Acetoin dehydrogenase, thymine PPi dependent, E1 component, beta subunit; Identified by match to PFAM protein family HMM PF02779.
    
 0.709
SAG0322
DNA-binding response regulator; Identified by match to PFAM protein family HMM PF00072.
  
 0.657
argF-1
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
     0.627
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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