Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SAG2127Sensor histidine kinase; Identified by match to PFAM protein family HMM PF02518. (431 aa)    
Predicted Functional Partners:
SAG2128
Response regulator; Identified by match to PFAM protein family HMM PF00072.
 
 
 0.963
SAG0881
Acetoin dehydrogenase, thymine PPi dependent, E3 component, dihydrolipoamide dehydrogenase; Identified by match to PFAM protein family HMM PF00070.
    
 0.882
SAG2124
Membrane protein, putative.
 
     0.789
SAG0394
Sensor histidine kinase; Identified by match to PFAM protein family HMM PF00512.
   
 0.686
ribA
Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.659
rbsB
Ribose ABC transporter, periplasmic D-ribose-binding protein; Identified by match to PFAM protein family HMM PF00532.
    
 0.658
argF-1
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
     0.639
SAG0342
Identified by match to PFAM protein family HMM PF00378.
   
 0.611
arcC-1
Carbamate kinase; Identified by match to PFAM protein family HMM PF00696; Belongs to the carbamate kinase family.
       0.580
SAG0322
DNA-binding response regulator; Identified by match to PFAM protein family HMM PF00072.
  
 0.534
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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