STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
fabH53-oxoacyl-[acyl-carrier-protein] synthase 3 protein 5; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (332 aa)    
Predicted Functional Partners:
kasA
3-oxoacyl-[acyl-carrier-protein] synthase 1; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 0.991
fabD
Malonyl CoA-acyl carrier protein transacylase.
 
 
 0.991
AIG79415.1
Hypothetical protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 
 0.986
bccA
Acetyl-/propionyl-coenzyme A carboxylase alpha chain.
 
 
 0.974
accA1
Acetyl-/propionyl-coenzyme A carboxylase alpha chain.
 
 
 0.972
AIG75369.1
Hypothetical protein.
  
 
 0.953
accD3
Acetyl CoA carboxylase beta subunit.
 
  
 0.933
AIG80002.1
acetyl/propionyl-CoA carboxylase, carboxyltransferase subunit.
 
  
 0.928
fabH4
3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 4; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
  
  
 
0.912
AIG77387.1
3-oxoacyl-(ACP) synthase III.
  
  
 
0.909
Your Current Organism:
Amycolatopsis japonica
NCBI taxonomy Id: 208439
Other names: A. japonica, Amycolatopsis japonicum, CIP 106801, DSM 44213, JCM 10140, NRRL B-24138, strain MG417-CF17
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