STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SED33643.1DSBA-like thioredoxin domain-containing protein. (206 aa)    
Predicted Functional Partners:
SEC15138.1
Arsenate reductase; Belongs to the ArsC family.
   
 
 0.867
mshD
Mycothiol synthase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
  
 
   0.787
mca-2
Mycothiol S-conjugate amidase; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
  
    0.776
mca
Mycothiol S-conjugate amidase; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily.
  
    0.775
SEB38279.1
Protein of unknown function.
  
     0.757
mshB
N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
  
     0.749
mshC
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
  
  
 0.661
SEB37911.1
NAD(P)H-dependent FMN reductase; Manually curated.
  
    0.616
SED33817.1
Hemoglobin.
 
  
 0.592
SED33669.1
Aminopeptidase N.
       0.583
Your Current Organism:
Amycolatopsis tolypomycina
NCBI taxonomy Id: 208445
Other names: A. tolypomycina, ATCC 21177, Amycolatopsis tolypomycina Wink et al. 2003, Amycolatopsis tolypophora, Amycolatopsis tolypophorous, DSM 44544, IFO 14664, IMSNU 20061, JCM 4936, NBRC 14664, NRRL B-24205, Streptomyces tolypophorus
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