STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SED68908.1Alkylated DNA repair protein (DNA oxidative demethylase). (207 aa)    
Predicted Functional Partners:
SEC92096.1
4-hydroxyphenylpyruvate dioxygenase.
   
    0.822
SED68928.1
Hypothetical protein.
       0.773
SEC59633.1
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
   
    0.730
SEC86671.1
Ketopantoate reductase.
   
    0.730
SED07379.1
Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
   
    0.730
SED68945.1
Alcohol dehydrogenase.
       0.559
SEC96227.1
methylated-DNA-[protein]-cysteine S-methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
 
  
 0.497
SED68966.1
Hypothetical protein.
       0.482
SEB32570.1
methylated-DNA-[protein]-cysteine S-methyltransferase.
  
  
 0.444
SEC96201.1
RNA polymerase sigma factor, sigma-70 family; Belongs to the sigma-70 factor family. ECF subfamily.
 
     0.430
Your Current Organism:
Amycolatopsis tolypomycina
NCBI taxonomy Id: 208445
Other names: A. tolypomycina, ATCC 21177, Amycolatopsis tolypomycina Wink et al. 2003, Amycolatopsis tolypophora, Amycolatopsis tolypophorous, DSM 44544, IFO 14664, IMSNU 20061, JCM 4936, NBRC 14664, NRRL B-24205, Streptomyces tolypophorus
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.