STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SED74500.1WD domain-containing protein, G-beta repeat-containing protein. (649 aa)    
Predicted Functional Partners:
SED17182.1
Hypothetical protein.
    
 0.924
SEC83536.1
Conserved hypothetical protein.
    
 0.862
SEC65619.1
Metallo-beta-lactamase family protein.
    
 0.833
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.824
SEC26807.1
Acetoin utilization protein AcuC.
    
 0.776
SEC25965.1
WD40 repeat.
  
    0.751
rplF
Large subunit ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
    
  0.680
SED09226.1
Caspase domain-containing protein.
  
 
  0.665
SEC26118.1
Hypothetical protein.
    
 0.661
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.647
Your Current Organism:
Amycolatopsis tolypomycina
NCBI taxonomy Id: 208445
Other names: A. tolypomycina, ATCC 21177, Amycolatopsis tolypomycina Wink et al. 2003, Amycolatopsis tolypophora, Amycolatopsis tolypophorous, DSM 44544, IFO 14664, IMSNU 20061, JCM 4936, NBRC 14664, NRRL B-24205, Streptomyces tolypophorus
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