STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEA54967.1Transcriptional regulator, IclR family. (239 aa)    
Predicted Functional Partners:
SEA52909.1
Sensor histidine kinase inhibitor, KipI family.
  
    0.963
leuC
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
  
 0.746
SDZ83108.1
Protein of unknown function.
  
     0.723
leuD
3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
  
    0.705
SDZ85141.1
Hypothetical protein.
  
     0.675
SEA08422.1
Transcriptional regulator, IclR family.
  
     0.513
SEA22101.1
Protein of unknown function.
  
     0.510
SEA63406.1
Transmembrane protein of unknown function.
  
     0.506
SEA21308.1
acetyl-CoA C-acetyltransferase.
  
 
 0.484
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
       0.478
Your Current Organism:
Actinomyces nasicola
NCBI taxonomy Id: 208480
Other names: A. nasicola, Actinomyces nasico, Actinomyces nasicola Hall et al. 2003, CCUG 46092, CIP 107668, DSM 19116, strain R2014
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