node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDZ85734.1 | SEA14839.1 | SAMN02910418_00418 | SAMN02910418_00992 | Formate C-acetyltransferase. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.983 |
SDZ85734.1 | SEA21308.1 | SAMN02910418_00418 | SAMN02910418_01101 | Formate C-acetyltransferase. | acetyl-CoA C-acetyltransferase. | 0.810 |
SDZ85734.1 | SEA62094.1 | SAMN02910418_00418 | SAMN02910418_02008 | Formate C-acetyltransferase. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.880 |
SDZ85734.1 | acsA | SAMN02910418_00418 | SAMN02910418_00515 | Formate C-acetyltransferase. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.772 |
SEA14839.1 | SDZ85734.1 | SAMN02910418_00992 | SAMN02910418_00418 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Formate C-acetyltransferase. | 0.983 |
SEA14839.1 | SEA21308.1 | SAMN02910418_00992 | SAMN02910418_01101 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | acetyl-CoA C-acetyltransferase. | 0.892 |
SEA14839.1 | SEA62066.1 | SAMN02910418_00992 | SAMN02910418_02007 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 4-hydroxy 2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 0.745 |
SEA14839.1 | SEA62094.1 | SAMN02910418_00992 | SAMN02910418_02008 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.865 |
SEA14839.1 | SEA62212.1 | SAMN02910418_00992 | SAMN02910418_02012 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase. | 0.726 |
SEA14839.1 | acsA | SAMN02910418_00992 | SAMN02910418_00515 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.932 |
SEA14839.1 | leuA | SAMN02910418_00992 | SAMN02910418_00277 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.939 |
SEA21308.1 | SDZ85734.1 | SAMN02910418_01101 | SAMN02910418_00418 | acetyl-CoA C-acetyltransferase. | Formate C-acetyltransferase. | 0.810 |
SEA21308.1 | SEA14839.1 | SAMN02910418_01101 | SAMN02910418_00992 | acetyl-CoA C-acetyltransferase. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.892 |
SEA21308.1 | SEA62066.1 | SAMN02910418_01101 | SAMN02910418_02007 | acetyl-CoA C-acetyltransferase. | 4-hydroxy 2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 0.701 |
SEA21308.1 | SEA62094.1 | SAMN02910418_01101 | SAMN02910418_02008 | acetyl-CoA C-acetyltransferase. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.791 |
SEA21308.1 | SEA62212.1 | SAMN02910418_01101 | SAMN02910418_02012 | acetyl-CoA C-acetyltransferase. | 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase. | 0.468 |
SEA21308.1 | acsA | SAMN02910418_01101 | SAMN02910418_00515 | acetyl-CoA C-acetyltransferase. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.879 |
SEA21308.1 | leuA | SAMN02910418_01101 | SAMN02910418_00277 | acetyl-CoA C-acetyltransferase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.847 |
SEA62066.1 | SEA14839.1 | SAMN02910418_02007 | SAMN02910418_00992 | 4-hydroxy 2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.745 |
SEA62066.1 | SEA21308.1 | SAMN02910418_02007 | SAMN02910418_01101 | 4-hydroxy 2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | acetyl-CoA C-acetyltransferase. | 0.701 |