STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yrrCPutative exonuclease with DNA/RNA helicase motif protein; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (829 aa)    
Predicted Functional Partners:
addA
ATP-dependent deoxyribonuclease subunit A; ATP-dependent DNA helicase.
  
 
 0.899
yrrB
Putative tetratricopeptide repeat family protein.
  
 
 0.874
dnaN
DNA polymerase III, subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.856
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
  
 
  0.686
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 
 0.642
pcrA
ATP-dependent DNA helicase PcrA.
  
 
 0.634
topB1
DNA topoisomerase 3.
  
 
 0.626
topA1
DNA topoisomerase 1; Belongs to the type IA topoisomerase family.
   
 
 0.626
topA2
DNA topoisomerase 1.
   
 
 0.626
dinG
Bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; 3'-5' exonuclease.
  
 0.607
Your Current Organism:
Carnobacterium sp. 174
NCBI taxonomy Id: 208596
Other names: C. sp. 17-4, Carnobacterium sp. 17-4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.