| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEB29149.1 | gcvPA | CAR_c04290 | CAR_c17600 | Putative aminomethyltransferase, family of glycine cleavage H protein. | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.994 |
| AEB29149.1 | gcvPB | CAR_c04290 | CAR_c17590 | Putative aminomethyltransferase, family of glycine cleavage H protein. | Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.998 |
| AEB29149.1 | gcvT | CAR_c04290 | CAR_c17620 | Putative aminomethyltransferase, family of glycine cleavage H protein. | Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
| AEB29149.1 | glyA | CAR_c04290 | CAR_c17040 | Putative aminomethyltransferase, family of glycine cleavage H protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.957 |
| AEB29149.1 | pdhA | CAR_c04290 | CAR_c09180 | Putative aminomethyltransferase, family of glycine cleavage H protein. | Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.631 |
| AEB29149.1 | pdhB | CAR_c04290 | CAR_c09190 | Putative aminomethyltransferase, family of glycine cleavage H protein. | Pyruvate dehydrogenase E1 component subunit beta. | 0.704 |
| AEB29149.1 | pdhC | CAR_c04290 | CAR_c09200 | Putative aminomethyltransferase, family of glycine cleavage H protein. | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. | 0.772 |
| AEB29149.1 | pdhD1 | CAR_c04290 | CAR_c09210 | Putative aminomethyltransferase, family of glycine cleavage H protein. | Dihydrolipoyl dehydrogenase. | 0.950 |
| AEB29149.1 | yusH | CAR_c04290 | CAR_c17610 | Putative aminomethyltransferase, family of glycine cleavage H protein. | Putative glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.918 |
| gcdH1 | pdhD1 | CAR_c16370 | CAR_c09210 | glutaryl-CoA dehydrogenase. | Dihydrolipoyl dehydrogenase. | 0.911 |
| gcvPA | AEB29149.1 | CAR_c17600 | CAR_c04290 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Putative aminomethyltransferase, family of glycine cleavage H protein. | 0.994 |
| gcvPA | gcvPB | CAR_c17600 | CAR_c17590 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.999 |
| gcvPA | gcvT | CAR_c17600 | CAR_c17620 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
| gcvPA | glyA | CAR_c17600 | CAR_c17040 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.966 |
| gcvPA | pdhC | CAR_c17600 | CAR_c09200 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex. | 0.411 |
| gcvPA | pdhD1 | CAR_c17600 | CAR_c09210 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Dihydrolipoyl dehydrogenase. | 0.919 |
| gcvPA | yusH | CAR_c17600 | CAR_c17610 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Putative glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
| gcvPB | AEB29149.1 | CAR_c17590 | CAR_c04290 | Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | Putative aminomethyltransferase, family of glycine cleavage H protein. | 0.998 |
| gcvPB | gcvPA | CAR_c17590 | CAR_c17600 | Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.999 |
| gcvPB | gcvT | CAR_c17590 | CAR_c17620 | Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |