| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| birA | dnaJ | CAR_c02360 | CAR_c10990 | Biotin acetyl-CoA-carboxylase ligase and biotin regulon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.437 |
| birA | glnA1 | CAR_c02360 | CAR_c13090 | Biotin acetyl-CoA-carboxylase ligase and biotin regulon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Glutamate--ammonia ligase. | 0.543 |
| birA | glnA2 | CAR_c02360 | CAR_c13110 | Biotin acetyl-CoA-carboxylase ligase and biotin regulon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Glutamate--ammonia ligase; Belongs to the glutamine synthetase family. | 0.543 |
| birA | glnR1 | CAR_c02360 | CAR_c13100 | Biotin acetyl-CoA-carboxylase ligase and biotin regulon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | HTH-type transcriptional regulator GlnR. | 0.474 |
| birA | rpoD | CAR_c02360 | CAR_c11690 | Biotin acetyl-CoA-carboxylase ligase and biotin regulon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.498 |
| dnaJ | birA | CAR_c10990 | CAR_c02360 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Biotin acetyl-CoA-carboxylase ligase and biotin regulon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.437 |
| dnaJ | glnR1 | CAR_c10990 | CAR_c13100 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | HTH-type transcriptional regulator GlnR. | 0.820 |
| dnaJ | rpoD | CAR_c10990 | CAR_c11690 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.562 |
| glnA1 | birA | CAR_c13090 | CAR_c02360 | Glutamate--ammonia ligase. | Biotin acetyl-CoA-carboxylase ligase and biotin regulon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.543 |
| glnA1 | glnA2 | CAR_c13090 | CAR_c13110 | Glutamate--ammonia ligase. | Glutamate--ammonia ligase; Belongs to the glutamine synthetase family. | 0.934 |
| glnA1 | glnR1 | CAR_c13090 | CAR_c13100 | Glutamate--ammonia ligase. | HTH-type transcriptional regulator GlnR. | 0.886 |
| glnA2 | birA | CAR_c13110 | CAR_c02360 | Glutamate--ammonia ligase; Belongs to the glutamine synthetase family. | Biotin acetyl-CoA-carboxylase ligase and biotin regulon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.543 |
| glnA2 | glnA1 | CAR_c13110 | CAR_c13090 | Glutamate--ammonia ligase; Belongs to the glutamine synthetase family. | Glutamate--ammonia ligase. | 0.934 |
| glnA2 | glnR1 | CAR_c13110 | CAR_c13100 | Glutamate--ammonia ligase; Belongs to the glutamine synthetase family. | HTH-type transcriptional regulator GlnR. | 0.819 |
| glnR1 | birA | CAR_c13100 | CAR_c02360 | HTH-type transcriptional regulator GlnR. | Biotin acetyl-CoA-carboxylase ligase and biotin regulon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.474 |
| glnR1 | dnaJ | CAR_c13100 | CAR_c10990 | HTH-type transcriptional regulator GlnR. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.820 |
| glnR1 | glnA1 | CAR_c13100 | CAR_c13090 | HTH-type transcriptional regulator GlnR. | Glutamate--ammonia ligase. | 0.886 |
| glnR1 | glnA2 | CAR_c13100 | CAR_c13110 | HTH-type transcriptional regulator GlnR. | Glutamate--ammonia ligase; Belongs to the glutamine synthetase family. | 0.819 |
| glnR1 | rpoB | CAR_c13100 | CAR_c24540 | HTH-type transcriptional regulator GlnR. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.650 |
| glnR1 | rpoD | CAR_c13100 | CAR_c11690 | HTH-type transcriptional regulator GlnR. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.504 |