upp protein (Carnobacterium sp. 174) - STRING interaction network

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upp

Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa)

Predicted Functional Partners:

udk1

0.998

udk2

0.981

pyrH

0.964

pyrF

0.964

pdp

0.938

atzC

0.929

pyrR

0.929

glyA

0.925

ywlF

0.826

guaA

0.746

Your Current Organism:

Carnobacterium sp. 174

NCBI taxonomy Id: 208596
Other names: C. sp. 17-4, Carnobacterium sp. 17-4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
atzC	pdp	CAR_c00490	CAR_c18520	N-isopropylammelide isopropylaminohydrolase.	Pyrimidine-nucleoside phosphorylase.	0.916
atzC	pyrR	CAR_c00490	CAR_c12110	N-isopropylammelide isopropylaminohydrolase.	Bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.	0.905
atzC	upp	CAR_c00490	CAR_c17030	N-isopropylammelide isopropylaminohydrolase.	Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.	0.929
glyA	guaA	CAR_c17040	CAR_c18400	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.801
glyA	pdp	CAR_c17040	CAR_c18520	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Pyrimidine-nucleoside phosphorylase.	0.409
glyA	upp	CAR_c17040	CAR_c17030	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.	0.925
glyA	ywlF	CAR_c17040	CAR_c14920	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	Ribose-5-phosphate isomerase B.	0.958
guaA	glyA	CAR_c18400	CAR_c17040	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.801
guaA	pdp	CAR_c18400	CAR_c18520	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Pyrimidine-nucleoside phosphorylase.	0.652
guaA	pyrF	CAR_c18400	CAR_c12170	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	0.756
guaA	pyrH	CAR_c18400	CAR_c10770	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.854
guaA	pyrR	CAR_c18400	CAR_c12110	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.	0.645
guaA	udk1	CAR_c18400	CAR_c08730	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Uridine kinase.	0.468
guaA	udk2	CAR_c18400	CAR_c21030	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Uridine kinase.	0.468
guaA	upp	CAR_c18400	CAR_c17030	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.	0.746
guaA	ywlF	CAR_c18400	CAR_c14920	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Ribose-5-phosphate isomerase B.	0.539
pdp	atzC	CAR_c18520	CAR_c00490	Pyrimidine-nucleoside phosphorylase.	N-isopropylammelide isopropylaminohydrolase.	0.916
pdp	glyA	CAR_c18520	CAR_c17040	Pyrimidine-nucleoside phosphorylase.	Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.	0.409
pdp	guaA	CAR_c18520	CAR_c18400	Pyrimidine-nucleoside phosphorylase.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.652
pdp	pyrR	CAR_c18520	CAR_c12110	Pyrimidine-nucleoside phosphorylase.	Bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.	0.918