| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEB29149.1 | gcvPA | CAR_c04290 | CAR_c17600 | Putative aminomethyltransferase, family of glycine cleavage H protein. | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.994 |
| AEB29149.1 | gcvPB | CAR_c04290 | CAR_c17590 | Putative aminomethyltransferase, family of glycine cleavage H protein. | Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.998 |
| AEB29149.1 | gcvT | CAR_c04290 | CAR_c17620 | Putative aminomethyltransferase, family of glycine cleavage H protein. | Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
| AEB29149.1 | glnA1 | CAR_c04290 | CAR_c13090 | Putative aminomethyltransferase, family of glycine cleavage H protein. | Glutamate--ammonia ligase. | 0.824 |
| AEB29149.1 | glnA2 | CAR_c04290 | CAR_c13110 | Putative aminomethyltransferase, family of glycine cleavage H protein. | Glutamate--ammonia ligase; Belongs to the glutamine synthetase family. | 0.824 |
| AEB29149.1 | glyA | CAR_c04290 | CAR_c17040 | Putative aminomethyltransferase, family of glycine cleavage H protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.957 |
| AEB29149.1 | pdhD1 | CAR_c04290 | CAR_c09210 | Putative aminomethyltransferase, family of glycine cleavage H protein. | Dihydrolipoyl dehydrogenase. | 0.950 |
| AEB29149.1 | pdhD2 | CAR_c04290 | CAR_c14250 | Putative aminomethyltransferase, family of glycine cleavage H protein. | Dihydrolipoyl dehydrogenase. | 0.952 |
| AEB29149.1 | purQ | CAR_c04290 | CAR_c23820 | Putative aminomethyltransferase, family of glycine cleavage H protein. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.823 |
| AEB29149.1 | yusH | CAR_c04290 | CAR_c17610 | Putative aminomethyltransferase, family of glycine cleavage H protein. | Putative glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.918 |
| gcvPA | AEB29149.1 | CAR_c17600 | CAR_c04290 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Putative aminomethyltransferase, family of glycine cleavage H protein. | 0.994 |
| gcvPA | gcvPB | CAR_c17600 | CAR_c17590 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.999 |
| gcvPA | gcvT | CAR_c17600 | CAR_c17620 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine. | 0.999 |
| gcvPA | glnA1 | CAR_c17600 | CAR_c13090 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Glutamate--ammonia ligase. | 0.837 |
| gcvPA | glnA2 | CAR_c17600 | CAR_c13110 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Glutamate--ammonia ligase; Belongs to the glutamine synthetase family. | 0.837 |
| gcvPA | glyA | CAR_c17600 | CAR_c17040 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.966 |
| gcvPA | pdhD1 | CAR_c17600 | CAR_c09210 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Dihydrolipoyl dehydrogenase. | 0.919 |
| gcvPA | pdhD2 | CAR_c17600 | CAR_c14250 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Dihydrolipoyl dehydrogenase. | 0.919 |
| gcvPA | purQ | CAR_c17600 | CAR_c23820 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.848 |
| gcvPA | yusH | CAR_c17600 | CAR_c17610 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Putative glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |