Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mvaAhydroxymethylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family. (428 aa)    
Predicted Functional Partners:
mvk
Mevalonate kinase.
 0.997
mvaS
hydroxymethylglutaryl-CoA synthase.
 
 0.997
mvaD
Diphosphomevalonate decarboxylase.
 
  
 0.851
fni
Isopentenyl diphosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
   
 0.806
mvaK
Phosphomevalonate kinase.
 
 
 0.674
AEB29256.1
Hypothetical protein.
   
 
 0.655
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase.
   
 
 0.655
thlA2
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
 
  
 0.502
ispA
Geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
 
 0.473
hepT
Heptaprenyl diphosphate synthase component II; Belongs to the FPP/GGPP synthase family.
  
 
 0.473
Your Current Organism:
Carnobacterium sp. 174
NCBI taxonomy Id: 208596
Other names: C. sp. 17-4, Carnobacterium sp. 17-4
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