| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEB29273.1 | gpsB | CAR_c05760 | CAR_c10480 | Dithiol-disulfide isomerase. | Cell cycle protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | 0.563 |
| AEB29273.1 | spxA3 | CAR_c05760 | CAR_c20440 | Dithiol-disulfide isomerase. | Regulatory protein spx; Belongs to the ArsC family. | 0.752 |
| comGC | gpsB | CAR_c06500 | CAR_c10480 | Pilin-like component of the DNA transport membrane platform. | Cell cycle protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | 0.454 |
| comGC | recU | CAR_c06500 | CAR_c10460 | Pilin-like component of the DNA transport membrane platform. | Holliday junction resolvase RecU; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. | 0.536 |
| comGC | spxA3 | CAR_c06500 | CAR_c20440 | Pilin-like component of the DNA transport membrane platform. | Regulatory protein spx; Belongs to the ArsC family. | 0.655 |
| comGC | yneF | CAR_c06500 | CAR_c10700 | Pilin-like component of the DNA transport membrane platform. | Hypothetical protein. | 0.701 |
| gpsB | AEB29273.1 | CAR_c10480 | CAR_c05760 | Cell cycle protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | Dithiol-disulfide isomerase. | 0.563 |
| gpsB | comGC | CAR_c10480 | CAR_c06500 | Cell cycle protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | Pilin-like component of the DNA transport membrane platform. | 0.454 |
| gpsB | recU | CAR_c10480 | CAR_c10460 | Cell cycle protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | Holliday junction resolvase RecU; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. | 0.814 |
| gpsB | spxA3 | CAR_c10480 | CAR_c20440 | Cell cycle protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | Regulatory protein spx; Belongs to the ArsC family. | 0.559 |
| gpsB | yjbH | CAR_c10480 | CAR_c07550 | Cell cycle protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | Putative thiol management oxidoreductase component. | 0.447 |
| gpsB | yneF | CAR_c10480 | CAR_c10700 | Cell cycle protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | Hypothetical protein. | 0.666 |
| recU | comGC | CAR_c10460 | CAR_c06500 | Holliday junction resolvase RecU; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. | Pilin-like component of the DNA transport membrane platform. | 0.536 |
| recU | gpsB | CAR_c10460 | CAR_c10480 | Holliday junction resolvase RecU; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. | Cell cycle protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. | 0.814 |
| recU | spxA3 | CAR_c10460 | CAR_c20440 | Holliday junction resolvase RecU; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. | Regulatory protein spx; Belongs to the ArsC family. | 0.619 |
| recU | yneF | CAR_c10460 | CAR_c10700 | Holliday junction resolvase RecU; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. | Hypothetical protein. | 0.761 |
| rpoA | rpoC | CAR_c24180 | CAR_c24530 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rpoA | rpoD | CAR_c24180 | CAR_c11690 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.962 |
| rpoA | spxA3 | CAR_c24180 | CAR_c20440 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Regulatory protein spx; Belongs to the ArsC family. | 0.732 |
| rpoA | yusI | CAR_c24180 | CAR_c04280 | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Putative oxidoreductase with thioredoxin domain; Belongs to the ArsC family. | 0.529 |