STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nirMCytochrome c-551 precursor; Electron donor for cytochrome cd1 in nitrite and nitrate respiration. (104 aa)    
Predicted Functional Partners:
nirS
Nitrite reductase precursor; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.998
nirC
Probable c-type cytochrome precursor; Monoheme c-type cytochrome.
  
  
 0.997
nirF
Heme d1 biosynthesis protein NirF; Required for the biosynthesis of heme d1 of nitrite reductase. Could have a dehydrogenase activity yielding sirohydrochlorin from precorrin-2 or dehydrogenation of propionate side chain C17.
  
  
 0.996
nirN
Probable c-type cytochrome; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
  
 0.994
nirL
Heme d1 biosynthesis protein NirL; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.987
nirJ
Heme d1 biosynthesis protein NirJ; Product name confidence: Class 1 (Function experimentally demonstrated in P. aeruginosa).
  
  
 0.986
nirD-2
Probable transcriptional regulator; Required for the biosynthesis of heme D1 of nitrite reductase.
  
    0.981
nirH
Conserved hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
  
  
 0.979
nirG
Probable transcriptional regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
  
 0.978
PA0510
Probable uroporphyrin-III c-methyltransferase; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the precorrin methyltransferase family.
  
  
 0.967
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.