STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mgtEProbable Mg transporter MgtE; Acts as a magnesium transporter. (482 aa)    
Predicted Functional Partners:
mgtA
Mg(2+) transport ATPase, P-type 2; Product name confidence: Class 2 (High similarity to functionally studied protein).
  
  
 0.679
exsA
Transcriptional regulator ExsA; Appears to be required for induction of exoenzyme S synthesis above a low basal level.
      
 0.587
PA0399
Cystathionine beta-synthase; Product name confidence: Class 2 (High similarity to functionally studied protein).
     
 0.579
fruI
Phosphotransferase system transporter enzyme I, FruI; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa; Belongs to the PEP-utilizing enzyme family.
     
 0.573
PA0912
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
  
    0.471
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.458
suhB
Extragenic suppressor protein SuhB; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the inositol monophosphatase superfamily.
     
 0.446
ptrB
Repressor, PtrB; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
  
 0.442
znuB
Permease of ABC zinc transporter ZnuB; Product name confidence: Class 2 (High similarity to functionally studied protein).
    
 
 0.440
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
 
   
 0.430
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.