STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PA1974Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences). (399 aa)    
Predicted Functional Partners:
PA1975
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
 
    0.955
ercS
ErcS; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
 
 
 0.955
exaA
Quinoprotein ethanol dehydrogenase; Catalyzes the oxidation of primary alcohols to the corresponding aldehydes, except for methanol, which is a very poor substrate. ExaA is also able to use secondary alcohols as well as amino alcohols like ethanolamine and l-amino-2-propanol, and aldehydes as substrates; Belongs to the bacterial PQQ dehydrogenase family.
 
  
 0.931
PA2019
Resistance-Nodulation-Cell Division (RND) multidrug efflux membrane fusion protein precursor; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
   
  
 0.889
PA1981
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
  
  
 0.882
PA2208
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
      
 0.882
PA1965
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
      
 0.880
exaB
Cytochrome c550; Is an essential component of the ethanol oxidation system that allows P.aeruginosa to grow on ethanol as the sole carbon and energy source. Is the direct electron acceptor of the quinoprotein ethanol dehydrogenase (QEDH).
 
    0.873
pqqE
Pyrroloquinoline quinone biosynthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
  
  
 0.866
PA2034
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
      
 0.827
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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