STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
czcCOuter membrane protein precursor CzcC; Product name confidence: Class 2 (High similarity to functionally studied protein). (428 aa)    
Predicted Functional Partners:
czcB
Resistance-Nodulation-Cell Division (RND) divalent metal cation efflux membrane fusion protein CzcB; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.998
czcA
Resistance-Nodulation-Cell Division (RND) divalent metal cation efflux transporter CzcA; Product name confidence: Class 2 (High similarity to functionally studied protein); Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
  
 0.995
copR
Two-component response regulator, CopR; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
 
 0.816
copS
Two-component sensor, CopS; Member of a two-component regulatory system.
  
  
 0.758
PA2524
Probable two-component sensor; Member of a two-component regulatory system.
 
  
 0.749
PA4820
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
   
    0.697
pcoA
Copper resistance protein A precursor; Product name confidence: Class 2 (High similarity to functionally studied protein).
  
  
 0.647
PA1048
Probable outer membrane protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
   
 
 0.603
pvdT
PvdT; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
   
 
 0.601
PA3523
Probable Resistance-Nodulation-Cell Division (RND) efflux membrane fusion protein precursor; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene); Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
 
 0.601
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.