STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
copSTwo-component sensor, CopS; Member of a two-component regulatory system. (443 aa)    
Predicted Functional Partners:
copR
Two-component response regulator, CopR; Class 1: Function experimentally demonstrated in P. aeruginosa.
 
 0.999
PA1437
Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
  0.982
PA2523
Probable two-component response regulator; Product name confidence: Class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene).
  
  0.982
irlR
Two-component response regulator; Product name confidence: Class 2 (High similarity to functionally studied protein).
  
  0.982
pcoA
Copper resistance protein A precursor; Product name confidence: Class 2 (High similarity to functionally studied protein).
 
 
 0.932
PA2807
Hypothetical protein; Product name confidence: Class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences).
  
  
 0.922
ptrA
Repressor, PtrA; Class 1: Function experimentally demonstrated in P. aeruginosa.
  
  
 0.910
parR
Two-component response regulator, ParR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
  
 
 0.906
amgR
AmgR; Product name confidence: Class 1: Function experimentally demonstrated in P. aeruginosa.
  
 
 0.879
pcoB
Copper resistance protein B precursor; Product name confidence: Class 2 (High similarity to functionally studied protein).
  
  
 0.875
Your Current Organism:
Pseudomonas aeruginosa
NCBI taxonomy Id: 208964
Other names: P. aeruginosa PAO1, Pseudomonas aeruginosa PAO1, Pseudomonas sp. PAO1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.